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Nuclear receptor coactivator 1

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Title: Nuclear receptor coactivator 1  
Author: World Heritage Encyclopedia
Language: English
Subject: Histone acetyltransferase, Androgen receptor, Glucocorticoid receptor, Aryl hydrocarbon receptor, Estrogen receptor alpha, C-Fos, PCAF, CREB-binding protein, C-jun, STAT3
Publisher: World Heritage Encyclopedia

Nuclear receptor coactivator 1

Nuclear receptor coactivator 1
PDB rendering based on 1oj5.
Available structures
PDB Ortholog search: RCSB
RNA expression pattern

The nuclear receptor coactivator 1 (

NCOA1 is also frequently called steroid receptor coactivator-1 (SRC-1).


Nuclear receptor coactivator 1 possesses a basic helix-loop-helix (bHLH) domain and has been shown to interact with Thyroid hormone receptor beta,[3][4] CIITA,[5] DDX17,[6] SNW1,[7] Androgen receptor,[8][9][10] STAT3,[11] CREB-binding protein,[12][13] Glucocorticoid receptor,[14][15] Peroxisome proliferator-activated receptor alpha,[16][17] TRIP4,[18] C-Fos,[19][20] STAT6,[21][22] PCAF,[23] PPARGC1A,[24] NFKB1,[19][25] Cyclin D1,[26] Estrogen receptor alpha,[6][12][27][28][29] DDX5[6] and C-jun.[19][20][30]


External links

  • Medical Subject Headings (MeSH)
  • C89

Further reading

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