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Hist1h3b

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Hist1h3b

Histone cluster 1, H3b
PDB rendering based on 1aoi.
Available structures
PDB Ortholog search: RCSB
Identifiers
HIST1H3B Gene
Orthologs
SpeciesHumanMouse

Histone H3.1 is a protein that in humans is encoded by the HIST1H3B gene.[1][2][3]

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.[4]

References

Further reading

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