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Hoxd13

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Hoxd13

Homeobox D13
Identifiers
Symbols  ; BDE; BDSD; HOX4I; SPD
External IDs GeneCards:
RNA expression pattern
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)
RefSeq (protein)
Location (UCSC)
PubMed search

Homeobox protein Hox-D13 is a protein that in humans is encoded by the HOXD13 gene.[1][2][3]

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in synpolydactyly and Brachydactyly.[3] The product of the mouse Hoxd13 gene plays a role in axial skeleton development and forelimb morphogenesis.[4]

See also

References

  1. ^ Acampora D, D'Esposito M, Faiella A, Pannese M, Migliaccio E, Morelli F, Stornaiuolo A, Nigro V, Simeone A, Boncinelli E (February 1990). "The human HOX gene family". Nucleic Acids Res 17 (24): 10385–402.  
  2. ^ McAlpine PJ, Shows TB (August 1990). "Nomenclature for human homeobox genes". Genomics 7 (3): 460.  
  3. ^ a b "Entrez Gene: HOXD13 homeobox D13". 
  4. ^ Davis AP, Capecchi MR (1 April 1996). "A mutational analysis of the 5' HoxD genes: dissection of genetic interactions during limb development in the mouse". Development 122 (4): 1175–85.  

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.



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