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Klf5

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Klf5

Kruppel-like factor 5 (intestinal)
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols  ; BTEB2; CKLF; IKLF
External IDs GeneCards:
RNA expression pattern
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)
RefSeq (protein)
Location (UCSC)
PubMed search

Krueppel-like factor 5 is a protein that in humans is encoded by the KLF5 gene.[1][2] This gene encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. Since the protein localizes to the nucleus and binds the epidermal growth factor response element, it is thought to be a transcription factor.[2]

Interactions

KLF5 has been shown to interact with Protein SET.[3]

See also

References

  1. ^ Sogawa K, Imataka H, Yamasaki Y, Kusume H, Abe H, Fujii-Kuriyama Y (May 1993). "cDNA cloning and transcriptional properties of a novel GC box-binding protein, BTEB2". Nucleic Acids Res 21 (7): 1527–32.  
  2. ^ a b "Entrez Gene: KLF5 Kruppel-like factor 5 (intestinal)". 
  3. ^ Miyamoto, Saku; Suzuki Toru, Muto Shinsuke, Aizawa Kenichi, Kimura Akatsuki, Mizuno Yoshiko, Nagino Tomoko, Imai Yasushi, Adachi Naruhiko, Horikoshi Masami, Nagai Ryozo (Dec 2003). "Positive and negative regulation of the cardiovascular transcription factor KLF5 by p300 and the oncogenic regulator SET through interaction and acetylation on the DNA-binding domain". Mol. Cell. Biol. (United States) 23 (23): 8528–41.  

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.



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