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Lanthanum carbonate

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Title: Lanthanum carbonate  
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Subject: Carbonates, Phosphate binders, Lanthanum compounds, Potassium binder, Calcium acetate/magnesium carbonate
Collection: Carbonates, Lanthanum Compounds, Phosphate Binders
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Lanthanum carbonate

Lanthanum carbonate
Names
IUPAC name
Lanthanum carbonate
Identifiers
 Y
ATC code V03
ChEMBL  N
ChemSpider  Y
Jmol-3D images Image
PubChem
Properties
La2(CO3)3
Molar mass 457.838 g/mol
Appearance White powder, hygroscopic
Density 2.6–2.7 g/cm3
Melting point decomposes
negligible
Solubility soluble in acids
Related compounds
Other anions
Lanthanum(III) oxide
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
 N  (: Y/N?)

Lanthanum carbonate, La2(CO3)3, is the salt formed by lanthanum(III) cations and carbonate anions. It is an ore of lanthanum metal, along with monazite.

Contents

  • Chemistry 1
  • Human and veterinary medicine 2
  • Other applications 3
  • References 4
  • External links 5

Chemistry

Lanthanum carbonate is used as a starting material in lanthanum chemistry, particularly in forming mixed oxides, for example

Human and veterinary medicine

Lanthanum carbonate is used in medicine as a phosphate binder.[1] As a medication it is sold under the trade name Fosrenol by the pharmaceutical company Shire Pharmaceuticals. Due to its large size (1000mg tablet is 2.2cm in diameter), it may be possible to choke on the tablet if it is not chewed. It is prescribed for the treatment of hyperphosphatemia, primarily in patients with chronic kidney disease. It is taken with meals and binds to dietary phosphate, preventing phosphate from being absorbed by the intestine. For cats suffering from hyperphosphatemia it is available under the trade name Renalzin by Bayer Animal Health.[2]

However, when lanthanum carbonate is used for treating hyperphosphatemia, its side effects, namely myalgia, muscular cramping, and peripheral edema, should be clinically monitored.[3]

Other applications

Lanthanum carbonate is also used for the tinting of glass, for water treatment, or as a catalyst for hydrocarbon cracking.

References

  1. ^ Editorial Staff (December 2004). "Lanthanum Carbonate". All Micromedex Systems. Micromedex, Inc. Archived from the original on 2007-09-14. Retrieved 2007-11-25. 
  2. ^ Bayer Animal Health (26 September 2008). "Bayer Animal Health launches Renalzin for Cats" (PDF). Retrieved 2008-09-30. 
  3. ^ Tonelli, Marcello; Pannu, Neesh; Manns, Braden (2010). "Oral Phosphate Binders in Patients with Kidney Failure". New England Journal of Medicine 362 (14): 1312.  

External links

  • Lanthanum - medlineplus.org
  • Fosrenol.com - the manufacturer's web site
  • Fosrenol - Drugs.com
  • Fosrenol - Medscape.com
  • PhosphorusControl.com - PhosphorusControl.com
  • Bayer Animal Health
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