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Orotidine 5'-monophosphate

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Title: Orotidine 5'-monophosphate  
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Language: English
Subject: Glycineamide ribonucleotide, 5-Aminoimidazole ribotide, Nucleotide, Biosynthesis, Uric acid
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Orotidine 5'-monophosphate

Orotidine 5'-monophosphate
CAS number
Jmol-3D images Image 1
Molecular formula C10H13N2O11P
Molar mass 368.191 g/mol
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 YesY   YesY/N?)

Orotidine 5'-monophosphate (OMP), also known as orotidylic acid, is a pyrimidine nucleotide which is the last intermediate in the biosynthesis of uridine monophosphate. OMP is formed from orotate and phosphoribosyl pyrophosphate by the enzyme Orotate phosphoribosyltransferase

In humans, the enzyme UMP synthase converts OMP into uridine 5'- monophosphate. If UMP synthase is defective, orotic aciduria can result.

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