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Title: Tfiif  
Author: World Heritage Encyclopedia
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Subject: Transcription factor, TATA box, Robert G. Roeder, General transcription factor, TATA-binding protein, Transcription factor II A
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general transcription factor IIF, polypeptide 1, 74kDa
Symbol GTF2F1
Alt. symbols TFIIF, BTF4, RAP74
Entrez HUGO OMIM RefSeq UniProt Locus p13.3
general transcription factor IIF, polypeptide 2, 30kDa
Symbol GTF2F2
Alt. symbols TFIIF, BTF4, RAP30
Entrez HUGO OMIM RefSeq UniProt Locus q14
general transcription factor IIF, polypeptide 2-like
Symbol GTF2F2L
Alt. symbols TFIIF
Entrez HUGO RefSeq Locus q31.22

Transcription factor IIF (TFIIF) is one of several general transcription factors that make up the RNA polymerase II preinitiation complex.[1][2][3]

Transcription Factor IIF is encoded by the

TFIIF binds to RNA PolII when the enzyme is already unbound to any other transcription factor, thus avoiding it from contacting DNA outside the promoter. Furthermore, TFIIF stabilizes the RNA polymerase II while it's contacting TBP and TFIIB.

See also


External links

  • Medical Subject Headings (MeSH)

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