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Thymidine triphosphate

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Title: Thymidine triphosphate  
Author: World Heritage Encyclopedia
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Subject: T7 DNA helicase, Helicos single molecule fluorescent sequencing, Trifluridine/tipiracil, Deoxyribonucleoside, Ribonucleoside
Collection: Nucleotides
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Thymidine triphosphate

Thymidine triphosphate
Identifiers
CAS number  N=
PubChem
ChemSpider  N=
MeSH
ChEMBL  N
Jmol-3D images Image 1
Properties
Molecular formula C10H17N2O14P3
Molar mass 482.168
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N

Deoxythymidine triphosphate (dTTP) is one of the four nucleoside triphosphates that are used in the in vivo synthesis of DNA. Unlike the other deoxyribonucleotide triphosphates, thymidine triphosphate does not contain the "deoxy" prefix in its name.[1] The corresponding ribonucleoside triphosphate is called 5-methyluridine triphosphate.

It can be used by DNA ligase to create overlapping "sticky ends" so that protruding ends of opened microbial plasmids may be closed up.

References

  1. ^ Coghill, Anne M.; Garson, Lorrin R., ed. (2006). The ACS style guide: effective communication of scientific information (3rd ed.). Washington, D.C.: American Chemical Society. p. 244.  
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