World Library  
Flag as Inappropriate
Email this Article

Transcription factor II E

Article Id: WHEBN0012589603
Reproduction Date:

Title: Transcription factor II E  
Author: World Heritage Encyclopedia
Language: English
Subject: GTF2E2, RNA polymerase II holoenzyme, NeuroD, EMX homeogene, Nur (biology)
Collection:
Publisher: World Heritage Encyclopedia
Publication
Date:
 

Transcription factor II E

general transcription factor IIE, polypeptide 1, alpha 56kDa
Identifiers
Symbol GTF2E1
Alt. symbols TF2E1
Entrez 2960
HUGO 4650
OMIM 189962
RefSeq NM_005513
UniProt P29083
Other data
Locus Chr. 3 q21-q24
general transcription factor IIE, polypeptide 2, beta 34kDa
Identifiers
Symbol GTF2E2
Alt. symbols TF2E2
Entrez 2961
HUGO 4651
OMIM 189964
RefSeq NM_002095
UniProt P29084
Other data
Locus Chr. 8 p12

Transcription factor II E (TFIIE) is one of several general transcription factors that make up the RNA polymerase II preinitiation complex.[1]

Transcription Factor II E is encoded by the GTF2E1 and GTF2E2 genes.[2][3][4][5] TFIIE is thought to be involved in DNA melting at the promoter: it contains a zinc ribbon motif that can bind single stranded DNA.[6]

See also

References

  1. ^ Lewin, Benjamin (2004). Genes VIII. Upper Saddle River, NJ: Pearson Prentice Hall. pp. p636–637.  
  2. ^ Ohkuma Y, Hashimoto S, Roeder RG, Horikoshi M (1992). "Identification of two large subdomains in TFIIE-alpha on the basis of homology between Xenopus and human sequences". Nucleic Acids Res. 20 (21): 5838.  
  3. ^ Heng HH, Xiao H, Shi XM, Greenblatt J, Tsui LC (1994). "Genes encoding general initiation factors for RNA polymerase II transcription are dispersed in the human genome". Hum. Mol. Genet. 3 (1): 61–4.  
  4. ^ Sumimoto H, Ohkuma Y, Sinn E, Kato H, Shimasaki S, Horikoshi M, Roeder RG (1991). "Conserved sequence motifs in the small subunit of human general transcription factor TFIIE". Nature 354 (6352): 401–4.  
  5. ^ Ohkuma Y, Sumimoto H, Hoffmann A, Shimasaki S, Horikoshi M, Roeder RG (December 1991). "Structural motifs and potential sigma homologies in the large subunit of human general transcription factor TFIIE". Nature 354 (6352): 398–401.  
  6. ^ Lee TI, Young RA (2000). "Transcription of eukaryotic protein-coding genes". Annu. Rev. Genet. 34: 77–137.  

External links


This article was sourced from Creative Commons Attribution-ShareAlike License; additional terms may apply. World Heritage Encyclopedia content is assembled from numerous content providers, Open Access Publishing, and in compliance with The Fair Access to Science and Technology Research Act (FASTR), Wikimedia Foundation, Inc., Public Library of Science, The Encyclopedia of Life, Open Book Publishers (OBP), PubMed, U.S. National Library of Medicine, National Center for Biotechnology Information, U.S. National Library of Medicine, National Institutes of Health (NIH), U.S. Department of Health & Human Services, and USA.gov, which sources content from all federal, state, local, tribal, and territorial government publication portals (.gov, .mil, .edu). Funding for USA.gov and content contributors is made possible from the U.S. Congress, E-Government Act of 2002.
 
Crowd sourced content that is contributed to World Heritage Encyclopedia is peer reviewed and edited by our editorial staff to ensure quality scholarly research articles.
 
By using this site, you agree to the Terms of Use and Privacy Policy. World Heritage Encyclopedia™ is a registered trademark of the World Public Library Association, a non-profit organization.
 



Copyright © World Library Foundation. All rights reserved. eBooks from Hawaii eBook Library are sponsored by the World Library Foundation,
a 501c(4) Member's Support Non-Profit Organization, and is NOT affiliated with any governmental agency or department.