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Ube2r2

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Title: Ube2r2  
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Subject: Ubiquitin-conjugating enzyme, DNAJC13, DNAJB4, DNAJC10, DNAJC11
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Ube2r2

Ubiquitin-conjugating enzyme E2R 2
Identifiers
Symbols  ; CDC34B; E2-CDC34B; UBC3B
External IDs GeneCards:
EC number
RNA expression pattern
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)
RefSeq (protein)
Location (UCSC)
PubMed search

Ubiquitin-conjugating enzyme E2 R2 is a protein that in humans is encoded by the UBE2R2 gene.[1][2] Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation.[2]

References

  1. ^
  2. ^ a b

Further reading

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