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Template for Toxicants Gene Expression Varies by Cell Type

By United Nations

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Book Id: WPLBN0000197183
Format Type: PDF eBook
File Size: 0.2 MB
Reproduction Date: 2005
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Title: Template for Toxicants Gene Expression Varies by Cell Type  
Author: United Nations
Language: English
Subject: Government publications, United Nations., United Nations. Office for Disarmament Affairs
Collections: Government Library Collection, Disarmament Documents
Publication Date:
Publisher: United Nations- Office for Disarmament Affairs (Unoda)


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Nations, U. (n.d.). Template for Toxicants Gene Expression Varies by Cell Type. Retrieved from

Government Reference Publication

Excerpt: Gene expression profiling shows that cells generally respond to toxicant stress by repressing genes that guide cell growth and inducing those that govern DNA repair and other protective functions. However, the specific genes repressed or induced vary, depending on the cell type and?according to research presented in this issue?the toxicant to which the cells are exposed [EHP 112:1607?1613]. Melissa Troester of the University of North Carolina at Chapel Hill and colleagues note that this study demonstrates the utility of microarrays in predictive toxicology.


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