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Plos One : the Unique Structure of the Apicoplast Genome of the Rodent Malaria Parasite Plasmodium Chabaudi Chabaudi, Volume 8

By Snounou, Georges

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Book Id: WPLBN0003968591
Format Type: PDF eBook :
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Reproduction Date: 2015

Title: Plos One : the Unique Structure of the Apicoplast Genome of the Rodent Malaria Parasite Plasmodium Chabaudi Chabaudi, Volume 8  
Author: Snounou, Georges
Volume: Volume 8
Language: English
Subject: Journals, Science, Medical Science
Collections: Periodicals: Journal and Magazine Collection (Contemporary)
Historic
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Publisher: Plos

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Snounou, G. (n.d.). Plos One : the Unique Structure of the Apicoplast Genome of the Rodent Malaria Parasite Plasmodium Chabaudi Chabaudi, Volume 8. Retrieved from http://www.hawaiilibrary.net/


Description
Description : The apicoplast, a non-photosynthetic plastid of apicomplexan species, has an extremely reduced but highly conserved genome. Here, the apicoplast genome of the rodent malaria parasite Plasmodium chabaudi chabaudi (Pcc) isolate CB was characterized. Although the set of genes in the genome is identical, the copy number of some tRNA genes differs between Pcc and other Plasmodium species because the Pcc DNA has only one rRNA/tRNA gene cluster, which is normally duplicated in other species. The location of the duplicated trnR(ACG) and trnM implies that one of the duplicated clusters in the ancestral molecule has been lost due to an intramolecular recombination event. The Pcc DNA occurs in two isoforms with an internal inversion between them. The presence of a unique variant in the duplicated trnT gene suggests that the two isoforms are interconvertible. This is the first report of the complete nucleotide sequence of a Plasmodium apicoplast DNA

 

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